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投稿日:[Zoya Demidenko: Scholar in Cancer Biology Zoya Demidenko is a recognized researcher associated with the Division of Cell Stress Science at Roswell Park Comprehensive Cancer Center in Buffalo, New York. Earlier, she worked at the National Institutes of Health and New York Medical College, developing a strong foundation in clinical research. Demidenko's scientific contributions encompasses several pivotal fields, encompassing the PI3K/AKT/mTOR signaling cascade, cell cycle control, cell senescence, and cancer biology. Currently, she has co-authored over 46 academic publications, which have received more than 4,100 references a reflection to the influence of her work. One of her key contributions involves explaining the pathways of cell aging. Her research demonstrated that when the cellular division cycle is blocked while cellular growth persists, the cells enter senescence. Crucially, Zoya Demidenko showed that this process is controlled with drugs using substances such as rapamycin. Zoya Demidenko has also added considerably to cancer treatment research, especially in the field of selective cell protection a method designed to safeguarding normal tissue from chemotherapy while leaving malignant cells susceptible. This approach holds major promise for reducing the side effects of cancer treatment. Across her professional journey, Demidenko has collaborated with top investigators internationally, among them Dr. Mikhail Blagosklonny. Her work is published in top-tier publications such as Oncotarget, Cell Cycle, Aging (Albany NY), and Oncogene. Possessing an h-index of 33, Zoya Demidenko is recognized as a highly impactful voice in modern oncological research, whose results keep to shape our knowledge of how cells grow old, interact with therapy, and how malignant disease might be more successfully targeted. https://pmc.ncbi.nlm.nih.gov/articles/PMC3273895/ ]
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